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From the identified articles we were
2018-10-23
From the identified articles, we were unable to demonstrate the total comorbidity between bipolar disorder and all anxiety disorders confidently, as some of the individual studies examined only one or two subtypes of the anxiety disorders, e.g. GAD or OCD. However, in twenty-nine out of fifty-two ar
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Following a thorough quality appraisal results
2018-10-23
Following a thorough quality appraisal, results from three studies were judged to be insufficiently credible for meta-analysis due to a lack of information presented about key components of their protocols (Bell and Orjasaeter, 1983; Fitzgerald et al., 1971; Kessel and Grossman, 1961). The quality o
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aa-utp br Author contributions br Disclosures br Introductio
2018-10-23
Author contributions Disclosures Introduction Cardiovascular disease is the leading cause of morbidity and mortality in individuals with diabetes, with a 2–4 fold higher risk of cardiovascular disease and up to 3 fold higher risk of mortality compared to those without diabetes (Fox et al.,
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Second when talking about risk associated
2018-10-23
Second, when talking about risk associated with alcohol consumption, it makes little sense to use words such as safe. Rather, risk needs to be examined for each disease outcome separately because pathways and risk differ from disease to disease, and the same amount of alcohol may be associated with
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Disclosure br High grade serous
2018-10-23
Disclosure High-grade serous ovarian cancer (HGSOC) has a high mortality rate because the disease is asymptomatic in early stages and is resistant to treatments. A novel modality for diagnosis in the early stages of carcinogenesis is needed. In this issue of , Hellner et al. present novel genetic
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This study has important limitations First participants came
2018-10-23
This study has important limitations. First, participants came from one academic medical center with its own patterns of clinic attendance, which may limit generalizability. The results may also differ by surgical specialty, which would be an interesting avenue for future investigation. Second, the
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Remarkably Cornelius et al report
2018-10-23
Remarkably, Cornelius et al. report for the first time HBV-neutralizing antibodies in all seven so-far tested human recipients of the BM32 vaccine, i.e., of preS antigen without other HBV antigens. Assay of neutralizing antibodies has been difficult because for long time the only HBV-susceptible cel
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The sympathetic regulation of GSIS should
2018-10-23
The sympathetic regulation of GSIS should be revisited as a therapeutic target for type 2 diabetes (Porte, 1969). Consistently, we observed that a PNx-induced increase in first-phase GSIS improved glycemic control in diabetic rats. More importantly, this surgical approach prevented β cell loss and s
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br Materials and Methods br Results
2018-10-23
Materials and Methods Results Discussion We report that increased GRK2 levels and functionality in either luminal or basal cancer buy Imatinib can drive the acquisition and maintenance of tumoral proliferation and survival. Elevated GRK2 protein levels are detected in different breast canc
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Treating Age related Macular Degeneration Using Human iPS Ce
2018-10-23
Treating Age-related Macular Degeneration Using Human iPS Cells Age-related macular degeneration (AMD) is a medical condition of the eye that results in blurred vision and/or a loss of central vision. The wet form of AMD – caused by abnormal blood vessel growth – is often treated using anti-VEGF me
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br Conclusion and Recommendations for Research The
2018-10-23
Conclusion and Recommendations for Research The emerging field of Nutritional Psychiatry offers promise for a new approach to both the prevention and treatment of disorders that account for the leading disability burden globally. Such investigations are also of relevance to neurodevelopmental (Bo
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Furthermore there are no studies exploring
2018-10-23
Furthermore, there are no studies exploring if additional anti-anaerobic therapy improves DFI outcome, and in this study, we find no correlation between the high relative abundance of obligate anaerobes and a greater tendency to fail antimicrobial therapy. The decision to use targeted antimicrobials
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br Identification of phosphorylation sites by NanoLC MS MS
2018-10-23
Identification of phosphorylation sites by NanoLC–MS/MS To determine phosphorylation sites of the identified phosphoprotein, we isolated total proteins from C101LAC and CO39 at 12h post-inoculation and mixed them in a 1:1 (w/w total protein) ratio. Protein JWH 073 was performed according to the
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br Data Xylogenesis a process of wood
2018-10-23
Data Xylogenesis (a process of wood fiber formation) is often characterized by two distinct stages: “early” and “late”. The first stage involves undifferentiated precursor ABT-737 that are characterized by their primary cell wall, whereas the later stage includes a succession of events including
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Esto explica que en M xico sea escasa
2018-10-22
Esto explica que en México sea escasa la publicación de libros y artículos en torno buy Sapitinib la disputa por la “prostitución”. Existen, sin duda, espléndidas investigaciones históricas sobre la “prostitución” y muy serias investigaciones sobre distintos aspectos del comercio sexual, además de l
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