• An immunohistochemical study revealed that the sigma recepto

  2018-11-05

  

  An immunohistochemical study revealed that the sigma-1 receptor is localized underneath the cholinergic boutons. It has been previously proven that two types of potassium channels, Kv2.1 and SK are located in the postsynaptic membrane of motoneuronal cholinergic synapses. These channels release pota

• To date the literature has been inconsistent

  2018-11-05

  

  To date, the literature has been inconsistent regarding the direction of impact between weight perceptions and health behaviours. That is, no consensus has been reached on whether perceptions of being overweight – or underweight, for that Z-YVAD-FMK manufacturer – foster or discourage PA and healthy

• Longitudinal analyses have also stressed

  2018-11-05

  

  Longitudinal analyses have also stressed the importance of taking into account the specific characteristics of the caring activity, for example the type of care provided (e.g. personal and/or instrumental) and the health characteristics of the person being cared for. Research on the provision of inf

• Consistent with other studies we found that

  2018-11-05

  

  Consistent with other studies, we found that compared to males, females were more likely to have suicidal ideation and suicidal plan (McKinnon et al., 2016; Sharma, Nam, Kim & Kim, 2015; Swahn et al., 2012). A study of suicidality in street children and adolescents in Ghana showed a highly significa

• Given the aim of forming groups to

  2018-11-05

  

  Given the aim of forming groups to comprise a specific ratio of faah inhibitors with/without challenges to optimise group functioning and dynamics, the difficulties in consistently achieving the specified composition were theorised to be important for intervention contribution and implementation fid

• br Methods br Results Table below presents baseline

  2018-11-05

  

  Methods Results Table 1 below presents baseline characteristics for intervention and matched control districts in 2010, the year before PBF began. While there are some differences in population size and the number of primary health facilities in matched districts, the number of facilities per

• It is with much pride that I

  2018-11-05

  

  It is with much pride that I am able to write the foreword to our first issue of the (SAJCE) published by Elsevier. The Journal was originally published by the South African Institution of Chemical Engineers. I remember receiving copies of the journal by post in the late 1990s as an undergraduate st

• br Conclusion br Introduction Platinum group metals PGMs are

  2018-11-05

  

  Conclusion Introduction Platinum group metals (PGMs) are applied in several different industries, hence the interest in developing methods for their separation (Kolekar and Anuse, 2002). Rhodium, for example, has been in demand in recent years since it is indispensable in automotive catalytic

• Ten years ago Shinya Yamanaka and

  2018-11-05

  

  Ten years ago Shinya Yamanaka and colleagues from Kyoto University (Japan) described the creation of induced pluripotent stem rsv virus (iPSCs), first from mice, then humans a year later. The ability to ‘reprogram’ mature cells into iPSCs by introducing genes that encode specific transcription fact

• The high burden of ocular

  2018-11-05

  

  The high burden of ocular disease in CKD can be explained, in part, by the sharing of risk factors common to both kidney and eye diseases such as age, smoking, hypertension, diabetes, raised serum cholesterol and obesity. Ocular diseases may also be directly linked to CKD via common pathogenic pathw

• There are a number of reasons

  2018-11-05

  

  There are a number of reasons that make the possibility to use blood-based miRNA signatures as diagnostic tools very attractive: i) cancer can be diagnosed in a minimally invasive way through a simple blood test; ii) a blood test does not require hospitalization and the access to complex and expensi

• Barry and colleagues have successfully used sophisticated

  2018-11-05

  

  Barry and colleagues have successfully used sophisticated and demanding in vivo recording techniques to correlate behavior and Madecassoside function at the mesoscale level. This is but one example of the power of those techniques that attempt the difficult task of bridging the behavior of single c

• In their manuscript in Psomas

  2018-11-05

  

  In their manuscript in , Psomas and colleagues used a combination of 68 markers of immune activation and inflammation and two independent hierarchical clustering analyses to identify 5 donor groups from among 120 HIV-infected virologic responders (). These donor groups were characterized using combi

• br Heating Up Immunologically Cold

  2018-11-05

  

  Heating Up Immunologically Cold Tumours With an Oncolytic Virus As discussed our immune systems have evolved elaborate mechanisms to react against invading pathogens and rapidly mount immune responses to eliminate the pathogen and in some instances, the cells they infect. OVs are natural pathogen

• A potential limitation of our

  2018-11-05

  

  A potential limitation of our study was the use of hospital controls as proxies of healthy people. Controls were admitted for a wide variety of routine conditions unrelated to tobacco and it is implausible that a high proportion of the controls with a detectable damaging TP53 mutation developed a ca

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