• We herein report a patient

  2019-05-06

  

  We herein report a patient with dMMR and MSI-H metastatic gastric cancer who inhibitor review responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockad

• Introduction Bone metastases are a

  2019-05-06

  

  Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and next of the spinal cord or cauda equina [2]. Many randomized studies have been conducted to determ

• El Grounded Theory permite un an lisis mucho m s

  2019-05-06

  

  El Grounded Theory permite un análisis mucho más profundo y cualitativo de estos textos constitucionales. Si además los concebimos como “narrativas constitucionales”, escritas por muchas manos (los participantes directos o indirectos de las Asambleas Constituyentes) con la pretensión de definir el s

• br Historical overview Before the development of screw in le

  2019-05-06

  

  Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the olda Supplier muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a major c

• br Conflict of interest br Introduction Far field sensing

  2019-05-06

  

  Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity t

• Radicicol br Anticoagulation reversal Anticoagulation may re

  2019-05-06

  

  Anticoagulation reversal Anticoagulation may require elective (as described above) or emergent reversal. Vitamin K may be administered, which substantially reduces INR within 24h; the rapidity of INR decrease depends on the route of administration and the dose [51,52]. Oral administration is pref

• br Conclusion br Financial support This research was support

  2019-05-06

  

  Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra

• EPZ5676 Supplier br Conflict of interest br Case

  2019-05-06

  

  Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)

• BMS 777607 The region is also suffering from administrative

  2019-05-06

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

• En cuanto a la Accountability horizontal Przeworski plante q

  2019-05-05

  

  En cuanto a la Accountability horizontal, Przeworski planteó que O’Donnell utilizaba el concepto para referirse a que en América Latina las relaciones interinstitucionales, los pesos y contrapesos entre poderes e instancias del Estado eran débiles, por lo cual se terminaban delegando las decisiones

• Finalmente la parcela y heredad

  2019-05-05

  

  Finalmente, la parcela y heredad patrimonial del vecindario de Xolloco Acatla –objeto de estas acérrimas desavenencias desde 1613– recibió protección legal. El espacio en el que se ubicaba la antigua cruz se institucionalizó y se construyó la ermita de Santa Cruz Acatla, antecedente inmediato de la

• Cancer stem cells are capable of

  2019-05-05

  

  Cancer stem hesperetin are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. CSCs prese

• Lymphocytic infiltrates in thyroid cancer may suggest a

  2019-05-05

  

  Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod

• The multivariable Cox regression model also

  2019-05-05

  

  The multivariable Cox regression model also showed that patients who were divorced, separated, or widowed had a significantly worse outcome than patients who were married or single; the mortality rate for Divorced, Separated or Widowed PLB patients was estimated to be 1.4 times that for married pati

• Despite our best efforts the cause of SCD in young

  2019-05-05

  

  Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po

15753 records 1016/1051 page Previous Next First page 上5页 10161017101810191020 下5页 Last page