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Subsequently more detailed mapping was performed to
2019-05-08
Subsequently, more detailed mapping was performed to identify the Purkinje potential preceding the QRS onset of the PVCs in their region of origin (Fig. 2B). Radiofrequency ablation was performed at the site of the earliest Purkinje potential preceding the local ventricular potential (Fig. 2C and D)
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Hydrogen peroxide H O is shown
2019-05-08
Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis
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br Introduction Once metastatic breast cancer cells
2019-05-08
Introduction Once metastatic breast cancer dna synthesis inhibitors are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and
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Two months from the initiation of dasatinib abnormal FDG
2019-05-07
Two months from the initiation of dasatinib, abnormal FDG uptake of the left femur tumor had disappeared. Examination of peripheral blood and the bone marrow examination showed that a complete cytogenetic response was achieved and a ratio of BCR-ABL to ABL on the international scale was 0.21%. Her d
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glucose transport proteins Reframing non communicable diseas
2019-05-07
Reframing non-communicable diseases (NCDs) to “spur a sense of urgency” and “focus attention on effective system-wide interventions” makes sense. With almost three-quarters of NCD deaths now occurring in low-income and middle-income countries (LMICs), the increasing burden of NCDs already has severe
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br Epidemiology Electrophysiological BrS phenotypes occur pr
2019-05-07
Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (by SAR405 rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. However, the BrS preva
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nimesulide br Methods br Results br Discussion Bisphosphonat
2019-05-07
Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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Interpretation AMWHO is a useful forum for students
2019-05-07
Interpretation AMWHO is a useful forum for students to improve their knowledge of global health issues, and sharpen their skills in diplomacy, communication, problem solving, and conflict resolution. Emory University (Atlanta, GA, USA) will host the next national AMWHO conference in October, 2016. E
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In our study ES SCLC
2019-05-07
In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun
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Kinase Inhibitor Library HF is associated with the down regu
2019-05-07
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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The STAR VT trial is a randomized trial
2019-05-07
The STAR-VT trial is a randomized trial examining the role of ablation in patient with an indication for ICD implantation [97]. The inclusion criteria targeting 562 patients with secondary prevention indications as well as primary prevention patients with inducible VT, where nonischemic cardiomyopat
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dub inhibitor The arrhythmia free rate was at
2019-05-07
The arrhythmia-free rate was 67%–91% at 1-year after multiple ablations depending on HF and LVEF status, although repeat ablations were required for more than half of the patients. One of the mechanisms responsible for tachyarrhythmia recurrences was conduction recovery in the PVs or linear lesions.
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In patients who develop bone metastases these
2019-05-07
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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In our study the levels of BALP PINP and CTx
2019-05-07
In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (ppurinergic receptor markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to predict the risk of SRE
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br Materials and methods br Results br Discussion Our
2019-05-07
Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a
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