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There remains a technical problem with a large amount of
2018-11-07
There remains a technical problem with a large amount of input DNA and/or poor quality DNA. The number of false positive events for some assays is increased by poor discrimination of the end point signal from other clusters within a 2-dimensional histogram in a multiplex assay. The insufficient sepa
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To improve peptide spectral matching sensitivity
2018-11-07
To improve peptide-spectral matching sensitivity and accuracy in obtaining MS2 peptide identification and spectral count quantitation mass spectra were searched using 3 search engines: Tide, INSPECT and MSGFDB each employing a different search methodology, and the spectral counts were integrated pro
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br Value of the data
2018-11-07
Value of the data Data This dataset collates the comprehensive proteomic data generated through a SILAC-based quantitative MS approach upon silencing the 65 tyrosine kinases expressed in MCF7 breast cancer Madecassic acid manufacturer [1]. In addition to the raw data files deposited in the Pr
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In the melting experiments with NMM and PDS
2018-11-07
In the melting experiments with NMM and PDS (Figs. 3 and 4), the ligands were added to pre-annealed ON solutions, and ON CD at 265/295nm was registered every 1°C across the 20–90°C temperature range. The heating rate was 1°C /min. The melting temperatures of GQs/imGQs were defined by performing a fi
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Metaplasticity is the dynamic regulation of the ability
2018-11-07
Metaplasticity is the dynamic regulation of the ability to induce activity-dependent synaptic plasticity and is governed by the prior history of activity (i.e. the plasticity of synaptic plasticity, Abraham and Bear, 1996). In empirical tests, synaptic metaplasticity is commonly defined as a shift i
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Finally there are questions concerning cognitive interpretat
2018-11-07
Finally, there are questions concerning cognitive interpretations that are routinely assigned to resting-state networks. Because profiles of activity that correlate with the instantiation of cognitive control (i.e., task-based maps of the CCN) appear convergent with maps of the CCN generated from re
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br Conclusions Although we have
2018-11-07
Conclusions Although we have focused specifically on cortical and hippocampal learning systems, there are other learning systems in the mitotic inhibitor that may relate to memory development. One important system includes the basal ganglia, which are highly responsive to reward and function as a
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To elucidate the development of neural mechanisms mediating
2018-11-07
To elucidate the development of neural mechanisms mediating age-related changes in behavior, it PR619 is important to map brain-behavior associations across age (Pfeifer and Allen, 2012). Poldrack has emphasized the importance of quantifying such associations precisely (Poldrack, 2014). However, mo
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In human adults the mu rhythm is sensitive to observation
2018-11-07
In human adults, the mu rhythm is sensitive to observation and mental imagery of orofacial movements (Muthukumaraswamy et al., 2006; Pfurtscheller et al., 2006; Spiegler et al., 2004), and the few studies that have investigated adult mu activity during observation of emotional facial expressions su
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br The Breadth of affect biased attention The proposed model
2018-11-07
The Breadth of affect-biased attention The proposed model accounts for the fact that while a perceptual sensitivity to particular cues may be normative and adaptive, displaying a large and fixed attention bias may be associated with psychopathology. For instance, in the anxiety literature, a perc
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br SES language and brain
2018-11-07
SES, language, and brain structure The brain undergoes significant changes over the course of development (Johnson et al., 2016). Synaptic density increases rapidly in the first few years of life, during which time neurons form connections and become organized into specialized functional regions.
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br Acknowledgments Bal zs Danyi author of
2018-11-06
Acknowledgments Balázs Danyi, author of Figs. 4, 5, and 7. This work was supported by the Hungarian Academy of Sciences under Grant Bolyai [number BO/00162/13/6]. Introduction: contextualizing Appreciative Inquiry (AI) Building on the ethos of the University of Strathclyde as “a place of use
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order S63845 Introduction Traumatic brain injury TBI
2018-11-06
Introduction Traumatic brain injury (TBI) is a leading cause of death and disability among children and young adults. It has limited treatment options. TBI survivors often suffer from severe disturbances regarding cognitive ability, memory, and neurological deficits. An unfavorable outcome rate con
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p2y receptor br Case reports The first patient was
2018-11-06
Case reports The first patient was 32 years old and underwent transsexual surgery about 10 years ago. Progressive voiding difficulty and micturition pain were noted about 5 years ago. She (the final gender on the identification card is female) came to our outpatient department for help and bougin
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Complete surgical excision is sufficient for mature and
2018-11-06
Complete surgical excision is sufficient for mature and Grade 1 immature teratomas. Optimal treatment by complete resection followed by close observation and follow-up, withholding chemotherapy until there is an evidence of disease recurrence, is recommended for Grade 2 and 3 immature teratomas. Thi
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