• If a structurally normal patient with polymorphic VT

  2019-04-19

  

  If a structurally normal patient with polymorphic VT/VF storm has a completely normal baseline ECG, the possible diagnosis includes CPVT and idiopathic VF. CPVT is an inherited disorder of intracellular Ca2+ handling, which can cause polymorphic VT/VF storms [10]. Abnormal SR Ca2+ release from defec

• A year old male with known dextrocardia and

  2019-04-19

  

  A 52-year-old male with known dextrocardia and CCTGA presented with a 2-month history of recurrent presyncope and effort intolerance. His examination revealed a resting pulse rate of 52beats/min (bpm) and a blood pressure of 130/80mmHg. The apex beat and heart sounds were appreciated on the right si

• Herweg et al evaluated the benefit of CRT in consecutive

  2019-04-19

  

  Herweg et al. [9] evaluated the benefit of CRT in 10 consecutive patients with NYHA class IV HF who were dependent on inotropic support. Their patients had received inotropic support for 146±258 days, and all patients were alive at the mean follow-up of 1088±284 days after CRT. They also reported an

• br Case report A year old man

  2019-04-19

  

  Case report A 73-year-old man with HCM experienced palpitations for 6 months. A 12-lead electrocardiogram (ECG) obtained at a medical clinic showed a first-degree atrioventricular block (PR interval, 260ms), left ventricular hypertrophy (LVH) with strain-type negative T waves in V2–6 leads, and m

• In advanced GIST patients where a course of

  2019-04-19

  

  In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest

• In the lead ECG after

  2019-04-19

  

  In the 12-lead ECG after successful RFCA (Fig. 1B), the QRS duration had decreased from 194ms to 84ms, and a significant first degree A-V block (PR interval, 274ms) was noted. The AH interval was 237ms as measured by the catheter placed at the bundle of His. On ECG performed the next day, the remar

• br Raising taxes on tobacco is

  2019-04-19

  

  Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2

• Second the intervention was delivered by community

  2019-04-19

  

  Second, the intervention was delivered by KB-R7943 mesylate volunteers and administered through a local non-governmental organisation (NGO) that was committed to ongoing community involvement. Intervention success is dependent on quality. In this Ugandan trial, quality was enhanced by the reputatio

• Pero el fuerte del comercio exterior argentino no

  2019-04-19

  

  Pero el fuerte del comercio exterior argentino no sólo estuvo centrado en la demanda china, también Latinoamérica fue un mercado importante para las exportaciones. En este sentido, Daniel Berrettoni y Mariángeles Polonsky sostienen que fue clave “la importancia y el dinamismo del mercado brasileño c

• Splicing machinery dysfunctions have been associated to

  2019-04-18

  

  Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu

• This report illustrates an unusual case of

  2019-04-18

  

  This report illustrates an unusual case of CMML which transformed to AML rapidly with emergence of the rare e6a2 fusion transcript. The possibility CML in blasts crisis was excluded as the CMML biopsy showed dysgranulopoiesis and lacked Ph chromosome and BCR-ABL1 fusion transcript. We further revi

• Heat shock proteins HSPs function as molecular chaperones

  2019-04-18

  

  Heat shock proteins (HSPs) function as molecular chaperones for various proteins and exhibit cytoprotective roles during several cellular stresses [8]. Human HSPs are classified into categories based on their molecular sizes, namely, HSP100, HSP90, HSP70, HSP60, HSP40, and small HSPs (15–30 kDa) inc

• Leong et al reported a

  2019-04-18

  

  Leong et al. reported a similar case of a short circuit in the Riata 1570 defibrillator lead, which manifested as unsuccessful defibrillation [10]. In this case, product analysis of generator indicated structural device damage owing to a short circuit in the defibrillation lead. Marenco et al. also

• Introduction Brugada syndrome is severe arrhythmia character

  2019-04-18

  

  Introduction Brugada syndrome is severe arrhythmia characterized by specific ST elevations in precordial leads and sudden ventricular fibrillation (VF), and the condition may result in sudden cardiac death [1–5]. By implanting defibrillation devices, also known as implantable cardioverter-defibrill

• br Commentary Her ECG showed a regular wide

  2019-04-18

  

  Commentary Her ECG showed a regular wide QRS complex tachycardia at a rate of 130 beats per minute. The morphology of the QRS complex exhibited the right BBB (RBBB) pattern with inferior axis. The duration of the QRS complex was 0.16s. P waves of sinus origin were not seen, presumably hidden in

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