• br Discovery of S PR as a CBA

  2019-05-04

  

  Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than

• Social determinants are the lived conditions ie social

  2019-05-04

  

  Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading

• mct2 inhibitor En esta ltima l nea mi

  2019-05-04

  

  En esta última línea, mi propósito es analizar la versión del episodio que, mct2 inhibitor principios del siglo xvii, ofreció el cronista de tradición indígena, Joan de Santa Cruz Pachacuti Yamqui Salcamaygua, y destacar en el estudio los elementos de carácter simbólico que proporciona su relato. Y,

• No se puede perder de vista que el vuelco

  2019-05-04

  

  No se puede perder de vista que el vuelco fundamental que han dado las expresiones identitarias alrededor del tópico del lugar del “negro” en la sociedad ha dado como resultado que la racialización ya no se erige con una connotación negativa sino que se asume como identidad, con la preocupación por

• South Africa was the first African country to implement the

  2019-05-04

  

  South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age

• The time to use the distraction osteogenesis

  2019-05-04

  

  The time to use the distraction–osteogenesis apparatus in children was suggested to be after infection eradication. We used the Ilizarov apparatus immediately following radical debridement to provide stability and prepare for distraction–compression osteogenesis 1 week later. Circular external fixa

• Another key challenge requires special attention in improvin

  2019-04-30

  

  Another key challenge requires special attention in improving maternal health in western China. On the basis of recent estimates, China has more than 250 million so-called rural-to-urban migrants who move from the countryside to cities to seek better paid jobs. A substantial number of these people c

• Univariate analysis for overall survival revealed that

  2019-04-30

  

  Univariate analysis for overall survival revealed that age (≤, >50 years), menopausal status, T-N stage, and histological tumor size were statistically significant factors for survival. Menopausal status was determined after two years of amenorrhea. In post-menopausal women, the disease-free surviva

• br Conclusion br Authors contribution br Competing

  2019-04-30

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• retinoic acid receptor Currently RFCA is indicated if pharma

  2019-04-30

  

  Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter

• MDV3100 Patients with heart failure are at

  2019-04-30

  

  Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa

• El proyecto literario del conocido escritor mexicano Ignacio

  2019-04-30

  

  El proyecto literario del conocido escritor mexicano Ignacio Manuel Altamirano (1834–1893) ha sido ampliamente documentado en los estudios del siglo . Su propósito fue claro: instruir e inspirar al pueblo mexicano, cansado y desilusionado por la situación inestable del México decimonónico y por el s

• lgk974 cost Data on the costs of mental disorders could

  2019-04-30

  

  Data on the costs of mental disorders could motivate changes in mental health services. In the UK, economists and clinical researchers showed that increasing access to evidence-based psychological services (eg, cognitive behavioural therapy) would be nearly cost-neutral for the UK Government because

• Esta simbiosis altamente pol mica en los

  2019-04-30

  

  Esta simbiosis altamente polémica en los terrenos de la narrativa, el ensayo y la crítica literaria coincidía con lo que unos años atrás había dado DMH-1 conocer: en 1972 apareció un volumen de estudios teóricos en torno del tema del realismo. No se trataba de textos escritos por nuestro autor, sino

• Parece claro entonces que la actuaci n de

  2019-04-29

  

  Parece claro, entonces, que la actuación de estos intelectuales —médicos, naturalistas, profesores, etc.— no se evalúa solamente desde la perspectiva inmanente de un campo disciplinario, sino que permite proyectar su imagen en el ámbito de lo público. De allí la construcción de figuras un tanto mono

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