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In our study ES SCLC
2019-05-07
In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun
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Kinase Inhibitor Library HF is associated with the down regu
2019-05-07
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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The STAR VT trial is a randomized trial
2019-05-07
The STAR-VT trial is a randomized trial examining the role of ablation in patient with an indication for ICD implantation [97]. The inclusion criteria targeting 562 patients with secondary prevention indications as well as primary prevention patients with inducible VT, where nonischemic cardiomyopat
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dub inhibitor The arrhythmia free rate was at
2019-05-07
The arrhythmia-free rate was 67%–91% at 1-year after multiple ablations depending on HF and LVEF status, although repeat ablations were required for more than half of the patients. One of the mechanisms responsible for tachyarrhythmia recurrences was conduction recovery in the PVs or linear lesions.
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In patients who develop bone metastases these
2019-05-07
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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In our study the levels of BALP PINP and CTx
2019-05-07
In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (ppurinergic receptor markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to predict the risk of SRE
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br Materials and methods br Results br Discussion Our
2019-05-07
Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a
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We herein report a patient
2019-05-06
We herein report a patient with dMMR and MSI-H metastatic gastric cancer who inhibitor review responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockad
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Introduction Bone metastases are a
2019-05-06
Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and next of the spinal cord or cauda equina [2]. Many randomized studies have been conducted to determ
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El Grounded Theory permite un an lisis mucho m s
2019-05-06
El Grounded Theory permite un análisis mucho más profundo y cualitativo de estos textos constitucionales. Si además los concebimos como “narrativas constitucionales”, escritas por muchas manos (los participantes directos o indirectos de las Asambleas Constituyentes) con la pretensión de definir el s
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br Historical overview Before the development of screw in le
2019-05-06
Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the olda Supplier muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a major c
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br Conflict of interest br Introduction Far field sensing
2019-05-06
Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity t
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Radicicol br Anticoagulation reversal Anticoagulation may re
2019-05-06
Anticoagulation reversal Anticoagulation may require elective (as described above) or emergent reversal. Vitamin K may be administered, which substantially reduces INR within 24h; the rapidity of INR decrease depends on the route of administration and the dose [51,52]. Oral administration is pref
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br Conclusion br Financial support This research was support
2019-05-06
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra
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EPZ5676 Supplier br Conflict of interest br Case
2019-05-06
Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)
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