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Finally it is highly interesting to
2019-05-20
Finally, it is highly interesting to note that human endogenous retroviruses have been suggested to play a role in the etiology of both MS and MPN [7,9]. Supporting this notion, both MS and MPN are treated with type 1 interferons, which have very potent antiviral and immunomodulating effects. Indeed
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br Introduction Bone marrow fibrosis is known to
2019-05-20
Introduction Bone marrow fibrosis is known to occur in several neoplastic and non-neoplastic conditions. Among neoplastic conditions such as acute leukemia, it is most often seen with acute megakaryoblastic leukemia [1]. Acute promyelocytic leukemia (APL) presenting with marrow fibrosis is a rare
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Surgical intervention remains obligatory for hemodynamic ins
2019-05-20
Surgical intervention remains obligatory for hemodynamic instability, including shock secondary to renal bleeding, complex lacerations, renal pelvic, or ureteral injury, plus certain renovascular conditions. The prolonged warm ischemia that may occur when under renal neoplasty usually results in irr
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In contrast median Cu level
2019-05-20
In contrast, median Cu level (0.73 mg/L) in our study was approximately 50% lower than that in maternal blood (1.47 mg/L). Our result is consistent with several previously published studies, which showed a 50–60% decrease in Cu level in the fetus. The observed decrease in fetal Cu, a major metallic
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For most health care professionals infectious disease modell
2019-05-18
For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used
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br Conflict of interest br Authors contributions br
2019-05-18
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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El estudio se realiza desde una perspectiva cualitativa a pa
2019-05-18
El estudio se realiza desde una perspectiva cualitativa, AN-2728 cost partir del análisis del discurso de entrevistas a miembros de los movimientos sociales, así como de declaraciones, discursos y otros textos vinculados tanto a gobiernos, como a los movimientos y sus respectivos proyectos y espacio
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Esta idea se reforz con
2019-05-18
Esta idea se reforzó con uno de los elementos identitarios oficiales de la organización, su propio escudo. La comil tomó cuatro de las características reconocibles del pgt histórico; es decir, las siglas, la estrella, la hoz y el martillo, y el círculo que enmarcó todos estos símbolos, mismos que de
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Emergency care inherently addresses the wide
2019-05-17
Emergency care inherently addresses the wide array of illness and injury, including traumatic injuries, surgical disease, acute complications of chronic illness (eg, strokes, myocardial infarction, diabetic ketoacidosis, complications of HIV, tuberculosis, hepatitis C, and other chronic infections),
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Heat shock facilitates the folding of various proteins as me
2019-05-17
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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However transparency has declined rather than improved
2019-05-17
However, transparency has declined rather than improved. A recent analysis in the ranked PEPFAR as very poor—50th of 67 aid agencies worldwide. The report noted that, “PEPFAR does not disclose information on contracts to prime partners and sub-partners in a machine-readable and open format consiste
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La descripci n que se hace del
2019-05-16
La descripción que se hace del accidente es distintiva de la forma en que los personajes de Ramos entran en contacto con los objetos, incapaces de percibir –y, por tanto, de razonar y discriminar- lo que los rodea se ven obligados Special Health Care Needs vivir en la angustia de irlo conociendo len
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OSA is a risk factor
2019-05-16
OSA is a risk factor for hypertension and stroke in particular [6,7]. Continuous positive airway pressure (CPAP) treatment reduces deaths and cardiovascular events, and improves hypertension control [8,9]. The role of CPAP therapy on the treatment of cardiac arrhythmia is still limited. Here, we rep
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br Introduction The early repolarization ER pattern
2019-05-16
Introduction The early repolarization (ER) pattern has been considered a benign electrocardiographic phenomenon affecting 2–5% of the general population and is most commonly seen in healthy young men and athletes [1–3]. Recent studies have challenged the view of this electrocardiogram (ECG) varia
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The data also revealed notable differences in practice patte
2019-05-16
The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone 3-Methyladenine detection; however, patients in Germany were most likely
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