• br Conflicts of interest br

  2023-08-29

  

  Conflicts of interest Introduction Arginase catalyzes the reaction in which l-arginine is converted to l-ornithine and urea. In humans, two arginase isoenzymes have been identified, arginase 1 and arginase 2, that differ in cellular location and tissue distribution [1]. Both arginase enzymes a

• Apoptosis a major process of programmed cell death and in

  2023-08-29

  

  Apoptosis, a major process of programmed cell death, and in response to many chemopreventive agents (Jeyamohan et al., 2016). In general, two major signaling pathways control apoptosis, namely, a pathway mediated by cell death receptor and a pathway mediated by mitochondrion, and possible drug targe

• Our previous studies and others

  2023-08-29

  

  Our previous studies and others have identified that the inhalational anesthetic isoflurane induces neuronal apoptosis via [Ca2+]i overload through the opening of synaptic voltage-dependent calcium channels (VDCCs) and the excessive Ca2+ release from the endoplasmic reticulum (Zhao et al., 2011; Zha

• Over expression of the inflammatory cytokines MMPs and COX a

  2023-08-29

  

  Over expression of the inflammatory cytokines, MMPs and COX-2 act as an important inducer of chronic inflammation. COX-2 catalyzes the biosynthesis of prostaglandins (PGs), and induced expression was observed in Pentylenetetrazole stimulated with pro-inflammatory cytokines or bacterial lipopolysacc

• Furthermore because most of foods and

  2023-08-29

  

  Furthermore, because most of foods and beverages have been consumed after processing, researchers have focused on the effects of processing (e.g. blanching, cooking, drying, cooling, freezing, high-pressure treatment, pulsed electric field) on total antioxidant capacity of foods. In general, there w

• br Acknowledgments br Protein microarrays

  2023-08-29

  

  Acknowledgments Protein microarrays were developed to provide miniaturized high-throughput tools to study protein function, AG-1024 and post-translational modifications. Just a few years ago, the seminal work performed in Stuart Schreiber's laboratory at Harvard University () and at Michael Sn

• Previous research showed that combination of chitosan

  2023-08-29

  

  Previous research showed that combination of chitosan and FR 236924 receptor nanocrystals (CNCs) can produce coating films with superior properties (Naseri, Mathew, Girandon, Fröhlich, & Oksman, 2015). CNCs are crystalline nanometer sized rod-like particles. It has been demonstrated that antimicrobi

• In conclusion there are only

  2023-08-29

  

  In conclusion, there are only a few experimental reports evaluating the influence of Dynorphin A mg on allergy. With the exception of studies using macrolides, most point to their harmful effect on the severity of this disease. Future studies will be crucial to define the impact of antibiotic use o

• Recently Kamoshita et al evaluated a

  2023-08-29

  

  Recently, Kamoshita et al. (2016) evaluated a mouse model of retinal neuronal disturbance with the intraperitoneal injection of LPS and found that treatment with AICAR suppressed the reduction of conical function and decreased mRNA levels of TNF-α as well as improved mRNA levels of the mitochondrial

• HyperScribe Poly (A) Tailing Kit Our research group has been

  2023-08-29

  

  Our research group has been involved by many years in the synthesis of new 2,3-benzodiazepin-4-ones (e.g. 1, Fig. 1) and in the characterization of their mechanism of action.15, 16, 17 Within the development of these compounds, we demonstrated that an improvement of AMPAR antagonism by 2,3-benzodiaz

• It has been reported that NLRP product caspase is increased

  2023-08-29

  

  It has been reported that NLRP3 product, caspase-1, is increased in the brains of AD patients and experimental AD animals. NLRP3- and caspase-1-deficient animals are resistant to experimental development of AD, and have decreased IL-1β production and significantly increased Aβ clearance (Heneka et a

• The correlation in the increase of BADH mRNA protein levels

  2023-08-29

  

  The correlation in the increase of BADH mRNA, protein levels, and enzyme activity, demonstrate that oxidation of betaine aldehyde by BADH is primordial to regulate the GB accumulation during physiological cardiac hypertrophy induced by pregnancy, this implies a major role because GB levels enhance c

• br Rapid nongenomic effects of corticosterone

  2023-08-29

  

  Rapid nongenomic effects of corticosterone in an amphibian model Studies in the model organism, the roughskin newt, Taricha granulosa, over 30 years ago led to the discovery that stress can rapidly (within minutes) suppress sexual behavior (amplectic clasping) of male T. granulosa, an effect that

• Given the profound expression of HT A and

  2023-08-28

  

  Given the profound β-Pompilidotoxin of 5-HT1A and 5-HT2A in the hippocampal CA1 region, and their potential to complex with mGluRs, the objective of this study was to examine if sleep deprivation alters the expression of 5-HT1A and 5-HT2A receptors and determine whether potential changes are revers

• There are however concerns of potential side

  2023-08-28

  

  There are however, concerns of potential side-effects that should also be taken into account. Even though some studies pointed towards a potentially greater radiosensitising effect in p53-deficient tumours, ATM inhibition radiosensitises (S)-(+)-Dimethindene maleate in general, which raises the conc

15094 records 243/1007 page Previous Next First page 上5页 241242243244245 下5页 Last page