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Heat shock facilitates the folding of various proteins as me
2019-05-17

Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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However transparency has declined rather than improved
2019-05-17

However, transparency has declined rather than improved. A recent analysis in the ranked PEPFAR as very poor—50th of 67 aid agencies worldwide. The report noted that, “PEPFAR does not disclose information on contracts to prime partners and sub-partners in a machine-readable and open format consiste
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La descripci n que se hace del
2019-05-16

La descripción que se hace del accidente es distintiva de la forma en que los personajes de Ramos entran en contacto con los objetos, incapaces de percibir –y, por tanto, de razonar y discriminar- lo que los rodea se ven obligados Special Health Care Needs vivir en la angustia de irlo conociendo len
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OSA is a risk factor
2019-05-16

OSA is a risk factor for hypertension and stroke in particular [6,7]. Continuous positive airway pressure (CPAP) treatment reduces deaths and cardiovascular events, and improves hypertension control [8,9]. The role of CPAP therapy on the treatment of cardiac arrhythmia is still limited. Here, we rep
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br Introduction The early repolarization ER pattern
2019-05-16

Introduction The early repolarization (ER) pattern has been considered a benign electrocardiographic phenomenon affecting 2–5% of the general population and is most commonly seen in healthy young men and athletes [1–3]. Recent studies have challenged the view of this electrocardiogram (ECG) varia
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The data also revealed notable differences in practice patte
2019-05-16

The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone 3-Methyladenine detection; however, patients in Germany were most likely
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Findings from the last major systematic review of the
2019-05-16

Findings from the last major systematic review of the global prevalence of echocardiographic rheumatic cisapride disease showed that the highest calculated regional prevalence was in sub-Saharan Africa (5·7 cases per 1000 people), indigenous people in the Pacific islands, Australia, and New Zealand
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Entre los cronistas y sin dejar
2019-05-16

Entre los cronistas, y sin dejar atrás esta concepción de la naturaleza y sin que se perciba un mayor conflicto, se advierte, en mayor o menor medida, un acentuado interés por los seres naturales y las “causas segundas”. La razón de esta falta de conflicto frontal obedece, por un lado, al reconocimi
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br Grant support This work was
2019-05-16

Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20
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br Discussion Debate persists about how to
2019-05-16

Discussion Debate persists about how to best define the ER ECG pattern. There is consensus regarding definition of the malignant form of ER as a J-point elevation that could be (or not) associated with ST elevation [1]. In this case, a clear J-point elevation was seen, particularly in lead III (F
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br Descripci n de las variantes Las variantes en los
2019-05-16

Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud
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br Alcohol and adipose tissue insulin resistance inflammatio
2019-05-16

Alcohol and adipose tissue insulin resistance, inflammation, and lipolysis Insulin is a hormone produced by pancreatic beta cells. It mediates carbohydrate, lipid, and protein metabolism in multiple organs, including the liver, adipose tissue, and skeletal muscle, to utilize and store ci-1033 fr
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La cr nica es en las obras
2019-05-15

La crónica es en las obras de Nájera, además de profusa, el género que imprimió mayor libertad creativa al contenido de sus temas, razón por la que sus múltiples intereses se vieron arropados más confortablemente en ella. La crónica de , otro de sus heterónimos más conocidos, fue entre otras cosas u
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The Millennium Development Goals MDGs have become key target
2019-05-15

The Millennium Development Goals (MDGs) have become key targets for the international Since first used in over the past 15 years. The MDGs have raised awareness, focused global efforts on agreed priorities, and empowered so-called development champions at country level. This progress was less strai
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br Point of care diagnostic tests POCTs
2019-05-15

Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and d
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